ASPOFAFF :: Journal - Volume 2 :: Volume 2 - Issue 1 :: Vol 2 - Iss 1 - Short Communication - Self Evaluation of Real Life Functioning in Bipolar Patients


	Home


	Shopping Cart


	Contact Us


	IRBD.ORG


	EUBF.ORG

All Enquiries:: +44 (0)20 8487 1421

Search:

Advanced search

Printable version

Categories

Help

ASPOFAFF :: Journal - Volume 2 :: Volume 2 - Issue 1 :: Vol 2 - Iss 1 - Short Communication - Self Evaluation of Real Life Functioning in Bipolar Patients

Vol 2 - Iss 1 - Short Communication - Self Evaluation of Real Life Functioning in Bipolar Patients #82

Self Evaluation of Real Life Functioning in Bipolar Patients Wyckaert S1, Pitchot W2, Hulselmans J3, Lecompte D4, De Bruyckere K5, Reiter S5 1UPC St.Jozef, KUL, Belgium 2CHU Liège, Belgium 3AZ Stuyvenberg Antwerp, Belgium 4CHU Brugmann, Brussels, Belgium 5Medical Department, Eli Lilly, Belgium Introduction: The aim of this study is to describe the clinical characteristics, possible prognostic factors and outcome of manic or hypomanic patients treated with olanzapine in a naturalistic setting, and to compare the physician’s evaluation with a patient’s self-evaluation. Methods: This was a multicenter, Belgian study, using an anonymous data collection form and patient questionnaire. All demographic and clinical data were collected at hospital discharge in patients who received a treatment with olanzapine for at least 2 weeks or in ambulatory patients after 4 weeks of treatment with olanzapine. In this publication we will present the data comparing the physician’s evaluation with that of the patient, both using the Clinical Global Impression-Improvement (CGI-I) rating scale. Results: Three hundred eighteen patients (55% female) received a treatment with olanzapine for an acute manic or hypomanic episode. Most (56%) patients had an age ranged between 35 and 55 years, and 19% were first episode patients. Diagnostic subtypes for mania were defined by the physician: 20% hypomania, 29% euphoric mania, 29% dysphoric mania and 22% mixed mania. Almost one third of the patients (31%) were treated with olanzapine in monotherapy (mean dose:16.6mg/d); 69% received olanzapine in combination therapy (mean dose:15.1mg/d). There was no difference in the use of olanzapine in mono- or combination therapy following mania subtype. Most (87%) patients received some kind of psycho-education. Physicians reported to be satisfied with the result of the treatment in 78% of the cases; 19% were partly satisfied. When patients were asked if the current treatment fulfilled their expectations, 58% answered yes, 35% partly and 7% no. A correlation was found between the CGI-I score (scale from 1 to 7) of the physician and that of the patient (r=0.511; p<0.001): mean score of the physician was: 2.07 (SD: 0.76) and of the patient: 2.28 (SD: 1.10); mean difference (CGI-I patient-physician): 0.21 (CI:0.10;0.32). There was a 50% match between the physician’s and patient’s CGI-I score; 41% of the patients evaluated themselves with only 1 point difference of the evaluation of the physician. Only 7% of the patients evaluated their improvement with =>2 points worse than the physician. The extent to which the patient evaluated himself differently from the physician (mean CGI-I patient–physician) was not different for first or multiple episode (p=0.733), but there was a trend for the diagnosis (p=0.083), with a more important difference in mean CGI-I in euphoric mania (0.33; CI:0.14;0.52), and there was a trend for a more pronounced difference in patients treated with olanzapine in combination therapy (0.26; CI:0.13;0.39) (p=0.077). Conclusions: This study suggests that 1 out of 2 manic patients rated himself similarly to his physician. Self-assessment can be complementary in helping understanding the needs and expectations of bipolar patients and consequently in a better patient-physician relationship and long-term treatment adherence.

Details

Price: €0.01

Options

Quantity

Add to cart

Send to friend

Your name: *

Your e-mail: *

Recipient's e-mail: *

Send to friend

Your cart

	Cart is empty

View cart
Checkout

Authentication

Username

Password

Recover password

If Javascript is disabled in your browser click here