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Journal - Volume 3
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Volume 3 - Issue 1 - Articles
:: Vol 3 - Iss 1 - Article - Acute and Transient Psychotic Disorders and bipolarity
Vol 3 - Iss 1 - Article - Acute and Transient Psychotic Disorders and bipolarity #94
Acute and Transient Psychotic Disorders and bipolarity
Andreas Marneros
Martin Luther University Halle-Wittenberg, Psychiatric Clinic
Correspondence and requests for reprints should be addressed to:
Prof. Dr. med. Dr. h. c. Andreas Marneros
Klinik und Poliklinik für Psychiatrie, Psychotherapie und Psychosomatik
Martin-Luther-Universität Halle-Wittenberg
06097 Halle
Germany
E-mail: andreas.marneros@medizin.uni-halle.de
Telephone: +49 345 557 3651
Fax: +49 345 557 3607
Word count: 4843
Conflicts of interest: none
Abstract
The concept of acute and transient psychoses is – together with that of schizoaffective disorders – a challenge of the Kraepelinian dichotomy. Although these conditions have some similarities to schizophrenia, they differ significantly from schizophrenia regarding onset, duration, prognosis, gender and premorbid adaptation. They show some similarities with bipolar disorders. They do not fit into the dichotomic concept.
Acute and Transient Psychotic Disorders, as defined by the ICD-10, are disorders which mainly concern females, with possible onset in all ages of adult life, but usually between the thirtieth and fiftieth year of life. Their onset is acute or even abrupt within 48 hours, but only rarely dependent on acute severe stress – contrary to former assumptions. The psychotic period is very short, with a mean of 17.5 days, in some cases even only one day. Their response to antipsychotic drugs is very good and their outcome is usually favourable in spite of the fact that they are usually recurrent. They differ from schizophrenia regarding the gender distribution, age at onset, premorbid level of functioning and social interactions. The level of postepisodic functioning and outcome is more favourable in ATPD than in schizophrenia. The syndrome shift in bipolar disorders (affective and schizoaffective) is much more pronounced than in schizophrenia, supporting the assumption that the relation between ATPD and affective (incl. schizoaffective) disorders is very close.
Key words
Acute psychotic disorders
Transient psychotic disorders
Antipsychotics
Gender
Outcome
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